PAT Analysis of particulate systems - from beaker to tube line and the reactor, inside of the process

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PAT Analysis of particulate systems - from beaker to tube line and the reactor, inside of the process

The Insitu PAT-Sensor is placed in the product, this may be within a laboratory beaker or directly within a supply line in pilot plant stations or process. The PAT-Sensor System ist started and the distribution is presented on screen within seconds. Changes during measurment phases are continuously displayed. The data are displayed as trend graph over time. Changes in production process can be detected at once and appropriate action can be taken accordingly. The Insitu PAT-Sensor Systems provide the opportunity  to transmit data digitally and/or analogically. 


Insitu PAT-Sensor Systems - Measuring Ranges and Concentration


Possible measuring ranges  <0.5 to 4000 µm



Volume concentration in Vol%

Measurement of


< 5%


Particle Distributions


5 -> 40%


Particle System Distributions


above 60%


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Applications

 

  • Homogenization
  • Polymerisation under EX-conditions
  • Dispersion
  • Granulation
  • Fermentation
  • Disaggregation
  • Flocculation
  • Particle and droplet size dependent crystallization



Process flow in practice







Practice


Particle Change


Result


1


Droplet formation


Droplets of different compunds are homogenized


Distinct distribution shift


2


Blending of pigments in emulsions


Distribution of pigments in the emulsion


After the emulsion is homogen, the emulsion raw data are substracted from the pigments+emulsion data


3


Distribution of droplet formation during polymerisation


Droplets get larger and stabilize


Fine fraction is reduced in favour of coarse fraction


4


Dry or wet grinding


Particles getting smaller


Distribution change - higher fine fraction


5


Nucleation at precipitation


Particles grow out of nano scale


Distribution change - higher fine fraction increasing


6


Particle breakage or splitting


Particles getting smaller


Distribution change - higher fine fraction - lower coarse fraction


7


Growth of particles


Particles getting larger


Distribution change - higher coarse fraction


8


Agglomeration and flocculation processes


Particles form particle systems


Distribution change - higher coarse fraction - lower fine fraction


9


Deaggregation


Particles dissolve


Particles dissolve


10


Change of shape at crystallisation


Particles deformate


Change of distribution function